2008 |  2007 |  2006 |  2005 |  2004 |  2003 |  2002 |  2001 |  2000 

2008

Rue, S.M., S.Mattei, S. Saksena, and S.D.Emr. 2008. Novel Ist1-Did2 complex functions at a late step in multivesicular body sorting. Mol. Biol. Cell, 19:475-484.

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2007

Efe, J.A., R.J. Botelho and S.D.Emr. 2007. Atg18 regulates organelle morphology and fab1 kinase activity independent of its membrane recruitment by phosphatidylinositol 3,5-bisphosphate. Mol. Biol. Cell, 18:4232-4244.

Saksena, S. J. Sun, T. Chu and S.D.Emr. 2007. ESCRTing proteins in the endocytic pathway. Trends Biochem. Sci., 32: 561-573.

Obita, T., Saksena, S. Ghazi-Tabatabai, S., Gill, D.J., Perisic, O., and S.D.Emr. 2007. Structural basis for selective recognition of ESCRT-III by the AAA ATPase Vps4. Nature, 449:735-739.

Gill, D.J., J. Sun, O. Perisic, DB Veprintsev, Y. Vallis, S.D. Emr, R.L. Williams. 2007. Structural Studies of phosphoinositide 3-kinase-dependent traffic to multivesicular bodies. Biochem. Soc. Symp., 74:47-57.

Gill, D.H., H.Teo, O. Perisidic, J. Sun, S.D. Emr and R.L. Williams. 2007.Structural insight into the ESCRT-I-II super-complex and its interaction networks on membranes. EMBO J., 26(2): 600-12

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2006

Chu, T., J. Sun, S. Saksena, and S.D. Emr. 2006. New component of ESCRT-I regulates endosomal sorting complex assembly. J. Cell Biol., 175(5): 815-23.

Morosova, N. Y. Liang, A.A. Tokagerev, S.H. Chen, R. Cox, J. Andrejic, Z. Lipatova, V.A. Sciorra, S.D. Emr and N. Segev. 2006. TRAPPII subunits are required for the specificity switch of a Ypt-Rab GEF. Nat. Cell Biol., 8: 1263-1269.

Tabuchi, M., A. Audhya, A.B. Parsons, C. Boone and S.D. Emr. 2006. The PI4,5P2 effectors Slm1 and Slim2 link calcineurin and sphingolipid signaling pathway. Mol. Cell Biol., 26: 5861-5875.

Kostelansky, M.S., J. Sun, S. Lee, J. Kim, R. Ghirlando, A. Hierro, S.D. Emr and J.H. Hurley. 2006. Structural and functional organization of the ESCRT-I trafficking complex.Cell, 125: 113-126.

Teo, H., D.J. Gill, J.Sun, O. Perisic, D.B. Veprintsev, Y. Vallis, S.D. Emr and R.L. Williams. 2006. Structures of the ESCRT-I core and the ESCRT-II GLUE domain: central role for GLUE domain in direct linking to ESCRT-I, phosphoinositides and ubiquitin. 2006. Cell, 125: 99-111.

Hurley, J.H., and S.D. Emr. 2006. The ECSRT complexes: structure and mechanism of a membrane-trafficking network. Ann. Rev. Biophys. Biomol. Struc., 35: 277-298.

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2005

Efe, J. A., F. Plattner, N. Hulo, D. Kressler, P. Linder, S. D. Emr and O. Deloche. 2005. Yeast Mon2p is a highly conserved protein that functions in the cytoplasm-to-vacuole transport pathway and is required for Golgi homeostasis. J. Cell Sci., 1118: 4751-4764.

Parrish, W. P., C. J. Stefan and S. D. Emr. 2005. PI 3-phosphate accumulation in triple lipid phosphatase-deletion mutants triggers lethal hyper-activation of the Rho1p/Pkc1p cell integrity MAP kinase pathway. J. Cell Sci., 118: 5589-5601.

Efe, J. A., R. J. Botelho and S. D. Emr. 2005. The Fab1 phosphatidylinositol kinase pathway in the regulation of vacuole morphology. Curr. Opin. Cell Biol., 4: 402-408.

Stefan, C. J., S. M. Padilla, A. Audhya and S. D. Emr. 2005. The phosphoinositide phosphatase Sjl2 is recruited to cortical actin patches in the control of vesicle formation and fission. Mol. Cell Biol., 25: 2910-2923.

Sciorra V.A., A.Audhya, A. B. Parsons, N. Segev, C. Boone and S.D. Emr. 2005. Synthetic genetic array analysis of the PtdIns 4-kinase Pik1p identifies components in a Golgi-specific Ypt31/rab-GTPase signaling pathway. Mol. Biol. Cell, 16: 776-793.

Shohdy, N., Efe, J.A., Emr, S.D. and Shuman, H.A. 2005. Pathogen effector protein screening in yeast identifies Legionella factors that interfere with membrane trafficking. PNAS, 102: 4866-4871.

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2004

Audhya, A., R. Loewith, A. B. Parsons, L. Gao, M. Tabuchi, H. Zhou, C. Boone, M. N. Hall and S.D. Emr. 2004. Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton. EMBO J., 23: 3747-3757.

Miller, A.L., M. Suntharalingam, S. L. Johnson, A. Audhya, S.D. Emr and S.R. Wente. 2004. Cytoplasmic IP6 production is sufficient for mediating the Gle1-mRNA export pathway. JBC, 279:51022-51032.

Stefan, C.J., and S.D. Emr. 2004. Vacuoles , Cell Architecture and Function. In: The Encyclopedia of Biological Chemistry, W. Lennarz and M.D. Lane (ed.) 4:331-336.

Hierro, A., Sun Ji, A. S. Rusnak, J. Kim, G. Prag, S.D. Emr and J. Hurley. 2004. Structure of the ESCRT-II endosomal trafficking complex. Nature, 9: 221-225

Parrish, W.R., C. S. Stefan, and S.D. Emr. 2004. Essential role for the myotubularin-related phosphatase Ymr1p and the synaptojanin-like phosphatases Sjl2p and Sjl3p in regulation of phosphatidylinositol 3-phosphate in yeast. Mol. Biol.Cell, 15: 3567-3579.

Baumeister, W., A. Bachmair, V. Chau, R. Cohen, P. Coffino, G. Demartino, R. Deshaies, J. Dohmen, S. Emr, D. Finley, R. Hampton, C. Hill, M. Hochstrasser, R. Huber, P. Jackson, S. Jentsch, E. Johnson, Y.T. Kwon, M. Pagano, C. Pickart, M. Rechsteiner, M. Scheffner, T. Sommer, W. Tansey, M. Tyers, R. Vierstra, A. Weismann, K.D. Wilkinson, and D. Wolf. 2004. Varshavsky's contributions. Science, 306: 1290-1292.

Alam S.L., Sun Ji, M. Payne, B. D.Welch, B. K. Blake, D. R. Davis, H. H. Meyer., S.D. Emr and W.I. Sundquist. 2004. Ubiquitin interactions of NZF zinc fingers. EMBO J., 23:1411-1421.

Yu, J.W., J.M. Mendrola, A. Audhya, S. Singh, D. Keleti, D.B. DeWald, D. Murray, S.D. Emr, M.A. Lemmon. 2004. Genome–wide analysis of membrane targeting by S. cerevisiae pleckstrin homology domains. Molecular Cell, 13: 677-688.

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2003

Katzmann, D.J., S. Sarkar, T. Chu, A. Audhya and S.D. Emr. 2003. Multivesicular body sorting: Ubiquitin ligase Rsp5 is required for the modification and sorting of carboxypeptidase S. Mol. Biol. Cell, 15: 468-480.

Rudge, S.A., D.M. Anderson and S.D. Emr. 2003. Vacuole size control: Regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase. Mol. Biol. Cell, 15: 24-36.

Odorizzi, G., D.J. Katzmann, M. Babst, A. Audhya and S.D. Emr. 2003. Bro1 is an endosome-associated class E Vps protein that functions in the MVB-sorting pathway in Saccharomyces cerevisiae. J. Cell Sci., 116: 1893-2003.

Katzmann, D.J., C.J. Stefan, M. Babst and S.D. Emr. 2003. Vps27 recruits ESCRT machinery to endosomes during MVB sorting. J. Cell Biol., 160: 413-423.

Audhya, A. and S.D. Emr. 2003. Regulation of PI4,5P2 synthesis by nuclear-cytoplasmic shuttling of the Mss4 lipid kinase. EMBO J., 22:4223-4236.

Stefan, C., A. Audhya and S.D. Emr. 2003. FYVE Domains in Membrane Trafficking and Cell Signaling. In: Handbook of Cellular Signaling, R. Bradshaw and E. Dennis (ed.), Academic Press, San Diego, CA., 2: 177-85.

Klionsky, D.J., J.M. Cregg, W.A. Dunn, S.D. Emr, Y. Sakai, A. Sibirny, S. Subramani, M. Thumm, M. Veenhuis and Y. Ohsumi. 2003. A unified nomenclature for yeast autophagy-related genes. Dev. Cell, 5: 539-45.

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2002

Katzmann, D.J., Odorizzi, G. and S. D. Emr. 2002. Receptor downregulation and multivesicular-body sorting. Mol. Cell. Bio. 3:893-905.

Malhotra, V. and S.D. Emr. 2002. Rothman and Schekman SNAREd by Lasker for trafficking. Cell, 111: :1-3.

Han, G.S., Audhya, A., Markley, D.J., S D. Emr and G. M. Carman. 2002. The Saccharomyces cerevisiae LSB6 Gene Encodes Phosphatidylinositol 4-kinase Activity. J. Biol. Chem, 277: 47709-47718.

Stefan, C.J., A. Audhya and S.D. Emr. 2002. The Yeast Synaptojanin-like proteins control the cellular distribution of phosphatidylinositol(4,5)-bisphosphate. Mol. Biol. Cell, 13: 542-557.

Audhya, A. and S. D. Emr. 2002. Stt4 PtdIns 4-kinase localizes to the plasma membrane and functions in the Pkc1-mediated MAP kinase cascade. Dev. Cell, : 2: 593-605.

Gary, J.D., T.K. Sato, C.J. Stefan C.J. Bonangelino, L.S.Weisman and S.D. Emr. 2002. Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member. Mol. Biol. Cell, 13: 1238-1251.

Bonangelino C.J., J.J. Nau, J.E. Duex, M. Brinkman, A.E. Wurmser, J.D. Gary, S.D. Emr, L.S. Weisman. 2002. Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p. J. Cell Biol., 18: 1015-1028.

Shih, S.C., D.J. Katzmann, J.D. Schnell, M. Sutanto, S.D. Emr and L. Hicke. 2002. Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosis. Nat. Cell. Biol., 4:389-393.

Babst, M., D.J. Katzmann, W.B. Snyder, B. Wendland, and S.D. Emr. 2002. Endosome-associated complex, ESCRT-II, Recruits transport machinery for protein sorting at the multivesicular body. Dev. Cell, 3: 283-289.

Babst, M., D.J. Katzmann, E.J. Estepa, T. Meerloo and S.D. Emr. 2002. ESCRT-III: An endosome-associated heterooligomeric protein complex required for MVB sorting. Dev. Cell, 3: 271-282.

Wurmser, A and S.D. Emr. 2002. Novel PI(3)P binding protein, Etf1, required for autophagy in yeast. J. Cell Biol., 158: 761-772.

Nice, D.C., T.K. Sato, P.E. Stromhaug S.D. Emr and D. Klionsky. 2002. Cooperative binding of the cytoplasm to vacuole targeting pathway proteins, Cvt13 and Cvt20, to PtdIns(3)P at the pre-autophagosomal structure is required for selective autophagy. J. Biol. Chem., 277: 30198-30207.

Burda, P., S.M. Padilla, S. Sarkar and S.D. Emr. 2002. Retromer function in endosome-to Golgi retrograde transport is regulated by the yeast Vps34 PtdIns 3-kinase. J. Cell Sci., 115: 3889-3900.

Zhong, Q., Lazar, C.S., Tronchere, H., Sato, T., Meerloo, T., Yeo, M., Songyang, Z., S. D. Emr and G. Gil. 2002. Endosomal localization and function of sorting nexin 1. PNAS, 99: 10: 6767-6772.

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2001

Katzmann, D.J., M. Bast and S.D. Emr. 2001. Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex. ESCRT-I. Cell, 106: 145-155.

Sato, T.K., M. Overduin, and S.D. Emr. 2001. Location, location, location: Membrane targeting directed by PX domains. Science, 294:1881-1885.

Simonsen, A., A.E. Wurmser, S.D. Emr and H. Stenmark. 2001. The role of phosphoinositides in membrane transport. Current Opinion in Cell Biol., 13: 485-492.

Costaguta, G., Stefan, C.J., Bensen, E.S., Emr, S.D., Payne, G.S. 2001. Yeast Gga Proteins Function with Clathrin in Golgi to Endosome Transport. Mol. Biol. Cell, 12: 1885-1896.

Peterson, M.R. and S.D. Emr. 2001. The class C Vps complex functions at multiple stages of the vacuolar transport pathway. Traffic, 2: 476-486.

Foti, M., A. Audhya and S. D. Emr. 2001. Sac1 lipid phosphatase and Stt4 PtdIns 4-kinase regulate a pool of PtdIns(4)P that functions in the control of the actin cytoskeleton and vacuole morphology. Mol. Biol. Cell, 12:2396-2411.

Cheever, M.L., T.K. Sato, T. de Beer, T. Kutateladze, S.D. Emr and M. Overduin. 2001. Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes. Nat. Cell. Biol., 3: 613-618.

Rieder, S.E. and .S.D. Emr. 2001. Isolation of subcellular fractions from the yeast Saccharomyces cerevisiae. Curr. Protoc. Cell Biol., Ch 3:, Unit 3.8.

Rieder, S.E. and .S.D. Emr. 2001. Overview of subcellular fractionation procedures for the yeast Saccharomyces cerevisiae. Curr. Protoc. Cell Biol., Ch 3:, Unit 3.7.

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2000

Darsow, T., G. Odorizzi and S. D. Emr. 2000. Invertase fusion proteins for analysis of protein trafficking in yeast. Methods in Enzymology, Vol. 327, 95-106.

Thorner, J., S.D. Emr and John N. Abelson (Eds.) (2000) "Applications of Chimeric Genes and Hybrid Proteins. Part A: Gene Expression and Protein Purification", Methods in Enzymology, Vol. 326, 617pp.

Thorner, J., S.D. Emr and J.N. Abelson (Eds.) (2000) "Applications of Chimeric Genes and Hybrid Proteins. Part B: Cell Biology and Physiology", Methods in Enzymology, Vol. 327, 672 pp.

Thorner, J., S.D. Emr and J.N. Abelson (Eds.) (2000) "Applications of Chimeric Genes and Hybrid Proteins. Part C: Protein-Protein Interactions and Genomics", Methods in Enzymology, Vol. 328, 666 pp..

Sato, T.K., P. Rehling, M.R. Peterson and S. D. Emr. 2000. Class C Vps protein complex regulates vacuolar SNARE pairing and is required for vesicle docking/fusion. Mol. Cell, 6: 661-671.

Wurmser, A.E., T.K. Sato and S.D. Emr. 2000. New component of the vacuolar class C Vps complex couples nucleotide exchange on the Ypt7 GTPase to SNARE-dependent Docking/Fusion. J. Cell Biol., 151: 551-562.

Klionsky, D.J.. and S.D. Emr. 2000. Autophagy as a regulated pathway of cellular degradation. Science, 290: 1717-1721.

Audhya, A, M. Foti, and S. D. Emr. 2000. Distinct roles for the yeast phosphatidylinositol 4-kinases, Stt4p and Pik1p, in secretion, cell growth, and organelle membrane dynamics .MBC., 11(8): 2673-2689.

Babst, M., G. Odorizzi, E.J. Estepa and S.D. Emr. 2000. Mammalian tumor susceptibility gene TSG101 and the yeast homologue Vps23p, both function in late endosomal trafficking.Traffic, 1 (3): 248-258.

Odorizzi, G., M. Babst, and S.D. Emr. 2000. Phosphoinositide signaling and the regulation of membrane trafficking in yeast, Trends Biochem. Sci., 2 (5): 229-235.

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